Ehrt
The lab is interested in the pathogenesis of Mycobacterium tuberculosis and explores the mechanisms by which this pathogen establishes and maintains persistent infections.
The lab is interested in the pathogenesis of Mycobacterium tuberculosis and explores the mechanisms by which this pathogen establishes and maintains persistent infections.
The Institute’s three main resources that enable the EIPM team to most efficiently match new, biologically-targeted therapies to patients who need it are next-generation genomics, biobanking, and computational biology. Our physician-scientists use the most ...
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The primary focus of my research is to understand the mechanical and metabolic drivers of immunity to enhance immunotherapeutic approaches to infectious diseases and cancer. Integration of immunometabolism and cellular mechanics underpins how cells ...
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The current interest of our team is to elucidate the links between cellular pathways of response to stress – including (but not limited to) autophagy, cellular senescence and multiple variants of regulated cell death ...
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The human microbiota, including the microbes living on/in the human body, modulates host biology in multiple ways. My research aims to study the chemistry and biology behind microbe-host interactions in the context of health ...
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My primary research interest is the identification of novel therapeutic approaches for targeting leukemia stem cells (LSCs) without harming normal hematopoietic stem cells (HSCs).
I am currently interested in employing predictive approaches (primarily through integrated analyses of public genomic datasets) that can be applied to various topics in cancer. These topics include: a) prediction of molecular markers for ...
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The main interest of the lab is centered on the basic understanding of nucleic acid recognition in autoimmunity and in particular on the potential clinical benefit of interfering with TLR signaling in human diseases. ...
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The Blander Laboratory studies the mechanisms by which the innate immune system detects and responds to perturbations in homeostasis at the molecular, cellular and organismal level. We study these responses in the context of ...
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I am interested in immune tolerance and it’s impact on T cell effector function. My goal is to investigate immunotherapeutics for cancer. In particular, these interests are centered around combinatorial applications of immunotherapy and ...
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