Archives

Matei

My research focuses on deciphering the role of exosomes in mediating the crosstalk between the host immune system and the tumor, and the mechanisms through which exosomes coax the immune system to contribute to ...
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McGraw

Insulin regulates the storage of dietary glucose by stimulating its uptake into muscle and fat. Insulin increases glucose uptake into these cells by recruiting vesicles containing the GLUT4 glucose transporter to the cell surface. ...
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Demaria

Sandra Demaria

Work in my laboratory is currently addressing the molecular mechanisms that are responsible for the increased antigenicity and adjuvanticity of cancer cells in irradiated tumors. We have recently identified mutation-generated CD8 T cell epitopes ...
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Dupnik

Kate Dupnik

My long-term goal as a physician-scientist is to explore differential human immune responses to mycobacterial pathogens, including Mycobacterium tuberculosis and M. leprae.

Ehrt

Sabine Ehrt

The lab is interested in the pathogenesis of Mycobacterium tuberculosis and explores the mechanisms by which this pathogen establishes and maintains persistent infections.

Elemento

Olivier Elemento

The Institute’s three main resources that enable the EIPM team to most efficiently match new, biologically-targeted therapies to patients who need it are next-generation genomics, biobanking, and computational biology. Our physician-scientists use the most ...
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Furler

Robert Furler

The primary focus of my research is to understand the mechanical and metabolic drivers of immunity to enhance immunotherapeutic approaches to infectious diseases and cancer. Integration of immunometabolism and cellular mechanics underpins how cells ...
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Galluzzi

Lorenzo Galluzzi

The current interest of our team is to elucidate the links between cellular pathways of response to stress – including (but not limited to) autophagy, cellular senescence and multiple variants of regulated cell death ...
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Guo

CJ Guo

The human microbiota, including the microbes living on/in the human body, modulates host biology in multiple ways. My research aims to study the chemistry and biology behind microbe-host interactions in the context of health ...
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Guzman

Monica Guzman

My primary research interest is the identification of novel therapeutic approaches for targeting leukemia stem cells (LSCs) without harming normal hematopoietic stem cells (HSCs).