The focus and long-term research goals of the Sonnenberg Laboratory are to interrogate the mechanisms that maintain a state of health in the human gastrointestinal tract. Ongoing research in the Sonnenberg Laboratory aims to ...
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My lab aims at exploring the immune-metabolic role of radiation therapy and to define the impact of TGFb and activin A in the radiation response of glioblastomas.
The Shen Lab lab investigates the genetic, epigenetic and metabolic mechanisms of cancer evolution. Our research is focused on understanding the role of PTEN in protecting the genome, maintaining chromatin architecture, suppressing tumorigenesis, and ...
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Development of the adaptive immune response and integration of DNA damage responses and immune responses.
We explore epigenetic mechanisms that are required to drive the humoral immune response, and how disruption of these mechanisms cause malignant transformation into lymphomas.
We use integrated preclinial and clinical investigations to determine the contribution of the tumor reprogramed immune microenvironments in lung cancer and breast cancer. We are investigating modalities including subablative radiation and agents that target ...
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The lab studies host-pathogen interactions, focusing on macrophages and Mycobacterium tuberculosis (Mtb). Most projects in the lab today fall into one or more of the following broad topics: host pathways controlling susceptibility and resistance ...
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I am interested in host pathogen interactions in human retrovirus infections, including HIV-1 and human endogenous retroviruses.
We are interested in the chemical biology of metabolism as a mediator of the host-pathogen interaction. We focus specifically on Mycobacterium tuberculosis and its ability to both asymptomatically infect and cause disease in humans.
To advance our understanding of the relationship between HIV and the human immune system primarily cytotoxic T-cells and natural killer cells.
