Microbiology & Immunology
Weill Cornell Medical - New York City
Interests: Dendritic Cells, Fibrosis, Human Health, Ifn, Immune Regulation, Immune-Mediated Disease, Immunity, Inflammation, Innate Receptors, Lupus, Signaling, TLR
The main interest of the lab is centered on the basic understanding of nucleic acid recognition in autoimmunity and in particular on the potential clinical benefit of interfering with TLR signaling in human diseases. We are using both human and mouse approaches and have focused on the role of the nucleic-acid specific TLR7, TLR8 and TLR9 in inflammation. The other main focus of the lab is to better understand the biology of human plasmacytoid dendritic cells.