My lab is focused on understanding basic principles of immunity against infection and age-related changes that alter immune responses in early life. We also are interested in determining how environmental factors (maternal diet, microbiome, ...
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We study the biology of Mycobacterium tuberculosis and HIV-1 infections in the context of our evolving appreciation of myeloid cell heterogeneity in vivo. Our studies extend to human subject analysis in Malawi and South ...
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My lab studies mechanisms of genome maintenance and consequences of genome instability. Such consequences include cancer, cellular senescence, impacts on stem cells, and lethal levels of inflammation.
My lab is interested in host-cell-virus interactions. We primarily study mammalian orthoreoviruses. Current projects include: mechanisms of viral compartmentalization and commandeering of the host translational machinery; viral mechanisms of counteracting the innate immune response; ...
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We study viruses of animals, focusing on those that have jumped from one host to another. The main subjects of study include the canine parvovirus, which emerged in 1978 to cause a pandemic in ...
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There is a fine balance between appropriate, host-protective, immune responses and dysregulated autoimmune and pathologic inflammation. The Leifer lab investigates how immune responses are induced and regulated with the hope of developing treatments to ...
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Studying host-parasite interactions that involves disciplines like pathology, immunology, molecular biology and gastroenterology. Developing diagnostics for veterinary parasites/pathogens. Studying biodiversity of parasites of North American wildlife.
My lab is currently focused on two areas of immunology, canine immune mediated disease and aging of the immune system. We are particularly interested in identifying mechanistic biomarkers to help improve, diagnosis, prognosis and ...
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Dr. Diel’s research focuses the molecular mechanisms underlying virus-host interactions and more specifically on the mechanisms underlying viral immune evasion that contribute to virus virulence and disease pathogenesis. My goal in studying virus-host interactions ...
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