My research program addresses 2 main interconnected areas: developmental immunology and immunodeficiencies, with focus on B cell generation and differentiation, and engaging discovery in basic immunology with direct application to clinical immunology. We study ...
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My research focuses on how health impacts the conservation of wild carnivores. My particular interest in immunology stems from the need to develop vaccination strategies (and potentially products) for delivery to threatened carnivore populations ...
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Clinical Trials: Novel hemostatic therapies for bleeding; novel immunosuppressive therapies for IMHA; interventional trials for sepsis management. Laboratory Research: Biomarkers in emergency and critical care, novel assays for diagnosis and management of hemorrhage and ...
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Dr. Guarino is interested in the development of novel serologic assays for the diagnosis of infection with viral and bacterial pathogens in companion and production animals. Of particular interest is the diagnosis of commonly ...
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We are interested in the genetic and environmental factors that regulate regulatory lymphocyte development and function, and how they interact to regulate immune homeostasis.
My research can be grouped into 3 broad categories: i) defining the role of DNA damage response mechanisms (DDR) in tumorigenesis and chemosensitivity as a means to identify biomarkers and therapeutic targets, ii) repurposing ...
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Our lab studies the role of DNA repair proteins in mediating germ cell development in mammals, the spermatogonial stem cell niche, DNA mismatch repair
The main focus of my research program is to elucidate key components in enveloped viruses and their host cells that: 1] mediate viral entry into cells, 2] elicit cell immune responses, and 3] mediate ...
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Immunological aspects of pregnancy; Immunogenetics; Immunity to Infectious Diseases. Primary species focus on the horse.
We are interested in the role of Tyrosine Kinases (TKs) in regulating the immune response, with the goal of using this information to manipulate immune responses. We are specifically interested in the Tec families ...
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