Archives

Kang

Josephine Kang

I am interested in the microbiome and how it impacts efficacy of immunotherapy and radiation. I am also studying prostate SBRT.

Khurana

The research interests of the lab fall under the broad categories of genomics, computational biology and systems biology. We participate in multiple international genomics consortia and collaborate with scientists at multiple institutes to develop ...
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Lu

Theresa Lu

The Lu lab studies the immune circuit in disease, seeking to understand how immune cell-vascular-stromal interactions in lymph nodes and skin lead to tissue injury and protection in the context of autoimmune diseases.

Lyden

David Lyden

My laboratory has focused much of its recent activity on understanding the role of tumor-secreted exosomes in cancer metastasis (Nature Medicine, 2012; Nature Cell Biology, 2015; Nature, 2015; Cancer Cell, 2016). My lab’s current ...
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Ma

Xiaojing Ma

We investigate (1) how UBR5, a novel protein ubiquitin ligase frequently altered in human cancers, promotes tumor metastasis by regulating epithelial to mesenchymal transition (EMT) in a cell intrinsic manner;(2) to identify UBR5’s E3 ...
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Matei

My research focuses on deciphering the role of exosomes in mediating the crosstalk between the host immune system and the tumor, and the mechanisms through which exosomes coax the immune system to contribute to ...
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Guo

CJ Guo

The human microbiota, including the microbes living on/in the human body, modulates host biology in multiple ways. My research aims to study the chemistry and biology behind microbe-host interactions in the context of health ...
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Guzman

Monica Guzman

My primary research interest is the identification of novel therapeutic approaches for targeting leukemia stem cells (LSCs) without harming normal hematopoietic stem cells (HSCs).

Demaria

Sandra Demaria

Work in my laboratory is currently addressing the molecular mechanisms that are responsible for the increased antigenicity and adjuvanticity of cancer cells in irradiated tumors. We have recently identified mutation-generated CD8 T cell epitopes ...
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Dupnik

Kate Dupnik

My long-term goal as a physician-scientist is to explore differential human immune responses to mycobacterial pathogens, including Mycobacterium tuberculosis and M. leprae.