I am interested in host pathogen interactions in human retrovirus infections, including HIV-1 and human endogenous retroviruses.
Our laboratory has had a longstanding interest in understanding the molecular mechanisms employed by lymphocytes to accurately respond to the signals that guide them along specific pathways.
We are interested in the chemical biology of metabolism as a mediator of the host-pathogen interaction. We focus specifically on Mycobacterium tuberculosis and its ability to both asymptomatically infect and cause disease in humans.
The goal of Dr. Salmon’s research is to identify predictors and determinants of disease phenotype in systemic lupus erythematosus (SLE) and related diseases, and to thereby identify targets for therapy. In SLE and other ...
We explore epigenetic mechanisms that are required to drive the humoral immune response, and how disruption of these mechanisms cause malignant transformation into lymphomas.
I have been working on a new technology in immune-oncology field leveraging on my expertise in gene expression analysis and genetic engineering. Recently, I defined a correlation between ICAM-1 expression and malignant features in ...
(1) Histone functional genetic models to study epigenetic regulation of mouse hematopoiesis and immune cell development. (2) Mechanisms and function of epigenetic memory of inflammation in hematopoietic stem cells. (3) “Signaling to chromatin” and ...
I am interested in the microbiome and how it impacts efficacy of immunotherapy and radiation. I am also studying prostate SBRT.
The research interests of the lab fall under the broad categories of genomics, computational biology and systems biology. We participate in multiple international genomics consortia and collaborate with scientists at multiple institutes to develop ...
The Lu lab studies the immune circuit in disease, seeking to understand how immune cell-vascular-stromal interactions in lymph nodes and skin lead to tissue injury and protection in the context of autoimmune diseases.