Vanpouille-Box
My lab aims at exploring the immune-metabolic role of radiation therapy and to define the impact of TGFb and activin A in the radiation response of glioblastomas.
My lab aims at exploring the immune-metabolic role of radiation therapy and to define the impact of TGFb and activin A in the radiation response of glioblastomas.
The Shen Lab lab investigates the genetic, epigenetic and metabolic mechanisms of cancer evolution. Our research is focused on understanding the role of PTEN in protecting the genome, maintaining chromatin architecture, suppressing tumorigenesis, and ...
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Development of the adaptive immune response and integration of DNA damage responses and immune responses.
Characterize host and bacterial pathways that are important in Mycobacterium tuberculosis survival in the host and identify targets whose inhibition will render Mtb more susceptible to host defenses.
The focus and long-term research goals of the Sonnenberg Laboratory are to interrogate the mechanisms that maintain a state of health in the human gastrointestinal tract. Ongoing research in the Sonnenberg Laboratory aims to ...
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We explore epigenetic mechanisms that are required to drive the humoral immune response, and how disruption of these mechanisms cause malignant transformation into lymphomas.
I have been working on a new technology in immune-oncology field leveraging on my expertise in gene expression analysis and genetic engineering. Recently, I defined a correlation between ICAM-1 expression and malignant features in ...
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We use integrated preclinial and clinical investigations to determine the contribution of the tumor reprogramed immune microenvironments in lung cancer and breast cancer. We are investigating modalities including subablative radiation and agents that target ...
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The lab studies host-pathogen interactions, focusing on macrophages and Mycobacterium tuberculosis (Mtb). Most projects in the lab today fall into one or more of the following broad topics: host pathways controlling susceptibility and resistance ...
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I am interested in host pathogen interactions in human retrovirus infections, including HIV-1 and human endogenous retroviruses.