We are interested in the chemical biology of metabolism as a mediator of the host-pathogen interaction. We focus specifically on Mycobacterium tuberculosis and its ability to both asymptomatically infect and cause disease in humans.
The goal of Dr. Salmon’s research is to identify predictors and determinants of disease phenotype in systemic lupus erythematosus (SLE) and related diseases, and to thereby identify targets for therapy. In SLE and other ...
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We explore epigenetic mechanisms that are required to drive the humoral immune response, and how disruption of these mechanisms cause malignant transformation into lymphomas.
Dr. Ivashkiv’s laboratory investigates the pathogenic mechanisms of cytokines in inflammatory and musculoskeletal conditions such as rheumatoid arthritis, osteolysis and orthopaedic implant loosening/failure, and systemic lupus erythematosus. He is interested in how cytokines and ...
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To advance our understanding of the relationship between HIV and the human immune system primarily cytotoxic T-cells and natural killer cells.
(1) Histone functional genetic models to study epigenetic regulation of mouse hematopoiesis and immune cell development. (2) Mechanisms and function of epigenetic memory of inflammation in hematopoietic stem cells. (3) “Signaling to chromatin” and ...
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I am interested in the microbiome and how it impacts efficacy of immunotherapy and radiation. I am also studying prostate SBRT.
The research interests of the lab fall under the broad categories of genomics, computational biology and systems biology. We participate in multiple international genomics consortia and collaborate with scientists at multiple institutes to develop ...
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Our work has focused on the molecular events important for immune cell development and function with a particular interest in the signaling events initiated by surface receptor engagement. We have been particularly interested in ...
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The Lu lab studies the immune circuit in disease, seeking to understand how immune cell-vascular-stromal interactions in lymph nodes and skin lead to tissue injury and protection in the context of autoimmune diseases.
