My lab is focused on understanding basic principles of immunity against infection and age-related changes that alter immune responses in early life. We also are interested in determining how environmental factors (maternal diet, microbiome, ...
Read More
We study the biology of Mycobacterium tuberculosis and HIV-1 infections in the context of our evolving appreciation of myeloid cell heterogeneity in vivo. Our studies extend to human subject analysis in Malawi and South ...
Read More
My lab develops and uses advanced optical techniques to observe and manipulate in vivo biological systems, with the goal of constructing a microscopic-scale understanding of normal and disease-state physiological processes in the central nervous ...
Read More
There is a fine balance between appropriate, host-protective, immune responses and dysregulated autoimmune and pathologic inflammation. The Leifer lab investigates how immune responses are induced and regulated with the hope of developing treatments to ...
Read More
Studying host-parasite interactions that involves disciplines like pathology, immunology, molecular biology and gastroenterology. Developing diagnostics for veterinary parasites/pathogens. Studying biodiversity of parasites of North American wildlife.
My lab tries to understand regulatory mechanisms of protein function, such as protein post-translational modifications and allosteric modulation, and to use the understanding to develop potential therapeutics for treating human diseases, including immune diseases.
My lab is currently focused on two areas of immunology, canine immune mediated disease and aging of the immune system. We are particularly interested in identifying mechanistic biomarkers to help improve, diagnosis, prognosis and ...
Read More
Our lab is interested in developing advanced biomaterials for agricultural and biomedical applications with a particular focus on cell replacement therapies for type 1 diabetes (T1D). Most of our work, ranging from material synthesis ...
Read More
Our lab studies Legionella infection and host interaction. Legionella are mainly environmental bacteria. Several species, in particular L. pneumophila and L. longbeachae, are pathogenic to humans Due to the development of artificial water systems, ...
Read More
Our research is focused on understanding, at the biochemical, molecular and cellular levels, how plants protect themselves against microbial pathogens. The major goal is to determine the mechanisms of action of salicylic acid (SA) ...
Read More
