My lab develops and uses advanced optical techniques to observe and manipulate in vivo biological systems, with the goal of constructing a microscopic-scale understanding of normal and disease-state physiological processes in the central nervous ...
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My lab studies mechanisms of genome maintenance and consequences of genome instability. Such consequences include cancer, cellular senescence, impacts on stem cells, and lethal levels of inflammation.
Given that a) the majority of the world is either over- or under-nourished; and b) diet and nutrition-related factors represent the largest proportion of risk factors for global mortality and morbidity, we often use ...
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I develop optical tools for imaging the behavior of cells within in vivo preparations. I apply these tools in many systems, but have particular interests in studying the effects of microvascular dysfunction in the ...
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Ong’s current research interests include the social determinants of health in later adulthood, particularly the role of social isolation and loneliness; the pathways linking positive emotions to quality living and health morbidities in both ...
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My lab is interested in host-cell-virus interactions. We primarily study mammalian orthoreoviruses. Current projects include: mechanisms of viral compartmentalization and commandeering of the host translational machinery; viral mechanisms of counteracting the innate immune response; ...
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We study viruses of animals, focusing on those that have jumped from one host to another. The main subjects of study include the canine parvovirus, which emerged in 1978 to cause a pandemic in ...
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I am interested in the interaction between the immune and endocrine systems, in particular how tissue-specific immune cells in reproductive and endocrine tissues regulate hormone production and action.
My lab is focused on understanding basic principles of immunity against infection and age-related changes that alter immune responses in early life. We also are interested in determining how environmental factors (maternal diet, microbiome, ...
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