I have been working on a new technology in immune-oncology field leveraging on my expertise in gene expression analysis and genetic engineering. Recently, I defined a correlation between ICAM-1 expression and malignant features in ...
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I am interested in host pathogen interactions in human retrovirus infections, including HIV-1 and human endogenous retroviruses.
Our laboratory has had a longstanding interest in understanding the molecular mechanisms employed by lymphocytes to accurately respond to the signals that guide them along specific pathways.
My lab is focused on understanding basic principles of immunity against infection and age-related changes that alter immune responses in early life. We also are interested in determining how environmental factors (maternal diet, microbiome, ...
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To advance our understanding of the relationship between HIV and the human immune system primarily cytotoxic T-cells and natural killer cells.
(1) Histone functional genetic models to study epigenetic regulation of mouse hematopoiesis and immune cell development. (2) Mechanisms and function of epigenetic memory of inflammation in hematopoietic stem cells. (3) “Signaling to chromatin” and ...
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Our work has focused on the molecular events important for immune cell development and function with a particular interest in the signaling events initiated by surface receptor engagement. We have been particularly interested in ...
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Immunological aspects of pregnancy; Immunogenetics; Immunity to Infectious Diseases. Primary species focus on the horse.
We are interested in the role of Tyrosine Kinases (TKs) in regulating the immune response, with the goal of using this information to manipulate immune responses. We are specifically interested in the Tec families ...
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The Blander Laboratory studies the mechanisms by which the innate immune system detects and responds to perturbations in homeostasis at the molecular, cellular and organismal level. We study these responses in the context of ...
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