I am currently the Associate Director of Precision Immunology in the Englander Institute of Precision Medicine and Professor of Physiology, Biophysics and Radiation Oncology at Weill-Cornell Medicine. Current efforts in my laboratory are focused ...
Read More
Characterize host and bacterial pathways that are important in Mycobacterium tuberculosis survival in the host and identify targets whose inhibition will render Mtb more susceptible to host defenses.
We investigate (1) how UBR5, a novel protein ubiquitin ligase frequently altered in human cancers, promotes tumor metastasis by regulating epithelial to mesenchymal transition (EMT) in a cell intrinsic manner;(2) to identify UBR5’s E3 ...
Read More
The main interest of the lab is centered on the basic understanding of nucleic acid recognition in autoimmunity and in particular on the potential clinical benefit of interfering with TLR signaling in human diseases. ...
Read More
