Although immune checkpoint blockade therapy has revolutionized cancer treatment, a subset of tumors, such as those of the breast, are still largely unresponsive. The Dongre Lab is focused on understanding mechanisms that can potentiate ...
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Dr. Formenti received her medical degree in Italy from the University of Milan. She is board certified in medical oncology, radiology and radiation oncology. A recognized leader in radiation oncology and breast cancer research, ...
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The objective of Dr. Gerlinde Van de Walle’s research is to open up new avenues towards therapeutic intervention by better understanding the pathogenesis of diseases important to veterinary and human medicine. To this end, ...
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My lab aims at exploring the immune-metabolic role of radiation therapy and to define the impact of TGFb and activin A in the radiation response of glioblastomas.
We use integrated preclinial and clinical investigations to determine the contribution of the tumor reprogramed immune microenvironments in lung cancer and breast cancer. We are investigating modalities including subablative radiation and agents that target ...
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My laboratory has focused much of its recent activity on understanding the role of tumor-secreted exosomes in cancer metastasis (Nature Medicine, 2012; Nature Cell Biology, 2015; Nature, 2015; Cancer Cell, 2016). My lab’s current ...
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The current interest of our team is to elucidate the links between cellular pathways of response to stress – including (but not limited to) autophagy, cellular senescence and multiple variants of regulated cell death ...
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