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DAY 1 – Monday, June 3, 2024
Bus Loading & Departure from Weill Cornell Campus to Cornell Ithaca Campus ( for Weill Cornell Medicine participants only)
7-11am: Bus departure from Weill Cornell (arrival at Ithaca, NY host campus about 11am)
1pm Welcome and Introductions (Symposium Co-Chairs Dr. Melody Zeng and Dr. Mandy McGeachy, Center for Immunology director Dr. Deborah Fowell)
Session 1 – Genomic profiling of immune cells in infection and inflammation
Moderators: Joseph Sun (NYC), Deb Fowell (Ithaca)
1:05-1:30pm Andrew Grimson (Professor, Ithaca)
Title: “The innate program of CD8+ T cells”
1:30-1:55pm Colleen Lau (Assistant Professor, Ithaca)
Title: “Epigenetic control of innate and adaptive immune memory”
1:55-2:20pm Simone Caielli (Assistant Professor, NYC)
Title: “An unconventional mechanism of IL-1b secretion that requires type I IFN in SLE monocytes”
2:20-2:35pm Ayshwarya Subramanian (Assistant Professor, Ithaca)
Title: “Macrophages in chronic tissue inflammation”
2:35-2:50pm Trainee talk – Endi Santosa, Sun lab (NYC)
Title: “Three-dimensional Chromatin Dynamics during Immune Memory Acquisition”
2:50-3pm Coffee break
Session 2 – Immune Influencers
Moderators: Ashley Nelson (NYC), Cindy Leifer (Ithaca)
3:00-3:25pm Greg Sonnenberg (Professor, NYC)
Title: “Innate immune determinants of intestinal physiology, tolerance, and inflammation”
3:25-3:50pm Nick Collins (Assistant Professor, NYC)
Title: “Nutritional optimization of anti-tumor immunity”
3:50-4:05pm Trainee talk – Geoffrey Markowitz, Vital lab (NYC)
Title: “Metabolic manipulation reveals heterogeneity in development of TCF1+ progenitor populations”
4:05-4:20pm Trainee talk – Alexander Brady, McGeachy lab (Ithaca)
Title: “Examining the outcomes of enhanced CD28 signaling in vivo using ‘humanized’ mice”
4:20-4:35pm Trainee talk – Zachery Hilt, Rudd lab (Ithaca)
Title: “Recent thymic emigrants are preferentially recruited into the memory pool during persistent infection”
Coffee break 4:35-5pm
5-6pm Keynote (sponsored by the Jill Roberts Institute for Research in IBD):
Donna Farber, Ph.D., Columbia University
Title: “Tissue-specific regulation of human immune responses”
Moderator: Melody Zeng
6:00-7:30pm ~ dinner & drinks (lower-level atrium) & Poster Session 1 – odd numbered abstracts (also #2 & #4) on display
7:30-9:00pm ~ Social Activities
DAY 2 – Tuesday, June 4, 2024
7:30am Breakfast
Session 3 – B cell regulation and function in infection and inflammatory disease
Moderators: Ria Goswami (NYC), Gary Koretzky (Ithaca)
8:30-8:55am Andrew Flyak (Assistant Professor, Ithaca)
Tital: “Gene-Encoded Antibody Neutralization of Hepatitis C Virus”
8:55-9:20am Sarah Caddy (Assistant Professor, Ithaca)
Title: “New appreciation for non-neutralizing antibodies”
9:20-9:45am Patrick Wilson (Professor, NYC)
Title: “Exploiting immune imprinting to improve influenza vaccines”
9:45-10:10am Emilie Grasset (Assistant Professor, NYC)
Title: “Exploring the role of IgA and mesenteric adipose tissue in anti-microbial immunity”
10:10-10:25am Trainee talk – Weiyao Wang, Delisa lab (Ithaca)
Title: “Glycosylated outer membrane vesicles as a tool for glycan-specific antibody discovery”
Coffee Break 10:25-10:45am
10:45-11:30am Trainee 3-minute elevator pitches (app for prizes)
Moderators: Mandy McGeachy and Melody Zeng
1. Christian Binuya – Permar Lab, NYC
2. Camille Holmes – Wagner Lab, Ithaca
3. Dan Hou – Lin Lab, Ithaca
4. Mingeum Jeong – Collins Lab, NYC
5. Anna Maria Kolarzyk – Lee Lab, Ithaca
6. Woan-Yu Lin – Iliev Lab, NYC
7. Noemi Linden – Jones Lab, NYC
8. Luisa Menezes-Silva – Collins Lab, NYC
9. David Sprott – Demaria Lab, NYC
10. Svena Verma – Merghoub Lab – NYC
11. Nathaniel Wright – Want Lab – Ithaca
12. Tiago Zilch – Fowell Lab, Ithaca
12:00– 3:30 pm ~ Boxed lunch and free/social/outdoor time – Robert H. Treman State Park trip
3:30pm Bus arrives back at the Vet College from the Robert H. Treman State Park trip
3:30-4:00pm ~ Coffee, beverages and cookies available, lower level of the atrium
Session 4 – Host-microbe interactions and mucosal immune regulation
Moderators: CJ Guo (NYC), Glenn E. Simmons Jr. (Ithaca)
4:00-4:25pm Pamela Chang (Associate Professor, Ithaca)
Title: “Deciphering the chemical crosstalk of host-gut microbiota interactions”
4:25 – 4:50pm Randy Longman (Associate Professor, NYC)
Title: “Innate lymphoid cells drive tumor associated neutrophils and granulopoiesis in colitis-associated cancer”
4:50-5:15pm Elizabeth Johnson (Associate Professor, Ithaca)
Title: “Dietary lipids as modulators of gut microbiome function”
5:15-5:40pm Iwijn De Vlaminck (Associate Professor, Ithaca)
Title: “Spatial mapping of host-microbe and host-microbiome interaction”
5:40-5:55 pm Trainee talk – Chongbo Yang, Blander lab (NYC)
Title: “The immune consequences of RIPK3-driven inflammatory cell death in the intestinal epithelium”
6:00-7:30pm ~ Light dinner & drinks lower level of the atrium & Poster Session 2 – even numbered abstracts on display
7:30-9:00pm ~ Social activities organized by trainee committee
Day 3 – Wednesday, June 5, 2024
7:30am Breakfast
Session 5: Immune regulation and immunotherapies in cancer
Moderators: Irina Matei (NYC), Anushka Dongre (Ithaca)
8:30-9:05am Plenary tallk: Taha Merghoub (Professor, NYC)
– Deputy Director of the Meyer Cancer Center at Weill Cornell Medicine
Title: “Developing means to overcome resistance to immune based therapies”
9:05-9:30am Juan Cubilos-Ruiz (Associate Professor, NYC)
Title: “Cytoskeletal control of intratumoral T cell metabolism and fate”
9:30-9:55am Roberta Zappasodi (Assistant Professor, NYC)
Title: “Tumor metabolism-driven cancer (immuno)therapies”
Coffee break: 9:55-10:05 am
10:05-10:30 am Abigail Overacre-Delgoffe (Assistant Professor, U. of Pittsburgh)
Title: “Diet and microbiota control of the tumor microenvironment”
10:30-10:45 am Trainee talk – Kimaya Bakhle, Dongre lab (Ithaca)
Title: “Targeting mesenchymal tumor cell-intrinsic factors sensitizes refractory tumors to immune checkpoint blockade therapy”
10:45-11:00 am Trainee talk – Inbal Wortzel, Lyden lab (NYC)
Title: “EV-DNA drives anti-tumor immunity in the pre-metastatic niche”
11:00-11:15 am Coffee break
11:15am-12:15pm Keynote: Greg M. Delgoffe Ph.D, University of Pittsburgh
Title: “Leveraging immunometabolism to improve cancer therapy”
Moderator: Mandy McGeachy
12:15-1:15pm Lunch
1:15-2:15pm Past inter-campus grant supported projects.
Moderator: Praveen Sethupathy
Julia Brown, Zeng lab (NYC)
Title: “Preterm infant microbiome impairs lung immune responses to respiratory viral infection”
Kristel Mon, Blander lab (NYC)
Title: A novel T cell vaccine candidate? Leveraging antigen cross-presentation to generate pan-Coronavirus specific CD8 T cells
Alexx Shumway, Sethupathy lab (Ithaca)
Title: Decreased miR-375 Marks Severe Ulcerative Colitis and Increases Pro-inflammatory State through Up-regulation of Cell Adhesion Molecule 1
Connor Kean, Grimson lab (Ithaca)
Title: “Determining the gene-regulatory impact of microbial exposure on central immune training”
2:15-3pm Announcement of 3-minute thesis winner, poster prize winners
Summary, Concluding Remarks (Co-Chairs)
3:00pm Bus departure
