The Shen Lab lab investigates the genetic, epigenetic and metabolic mechanisms of cancer evolution. Our research is focused on understanding the role of PTEN in protecting the genome, maintaining chromatin architecture, suppressing tumorigenesis, and ...
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Development of the adaptive immune response and integration of DNA damage responses and immune responses.
Characterize host and bacterial pathways that are important in Mycobacterium tuberculosis survival in the host and identify targets whose inhibition will render Mtb more susceptible to host defenses.
The focus and long-term research goals of the Sonnenberg Laboratory are to interrogate the mechanisms that maintain a state of health in the human gastrointestinal tract. Ongoing research in the Sonnenberg Laboratory aims to ...
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My lab aims at exploring the immune-metabolic role of radiation therapy and to define the impact of TGFb and activin A in the radiation response of glioblastomas.
Our laboratory has had a longstanding interest in understanding the molecular mechanisms employed by lymphocytes to accurately respond to the signals that guide them along specific pathways.
We are interested in the chemical biology of metabolism as a mediator of the host-pathogen interaction. We focus specifically on Mycobacterium tuberculosis and its ability to both asymptomatically infect and cause disease in humans.
The goal of Dr. Salmon’s research is to identify predictors and determinants of disease phenotype in systemic lupus erythematosus (SLE) and related diseases, and to thereby identify targets for therapy. In SLE and other ...
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We explore epigenetic mechanisms that are required to drive the humoral immune response, and how disruption of these mechanisms cause malignant transformation into lymphomas.
I have been working on a new technology in immune-oncology field leveraging on my expertise in gene expression analysis and genetic engineering. Recently, I defined a correlation between ICAM-1 expression and malignant features in ...
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