Holowka
Immune cell signaling.
Immune cell signaling.
Molecular and Cellular Mechanisms of Neurodegneration
We are interested in the genetic and environmental factors that regulate regulatory lymphocyte development and function, and how they interact to regulate immune homeostasis.
My research can be grouped into 3 broad categories: i) defining the role of DNA damage response mechanisms (DDR) in tumorigenesis and chemosensitivity as a means to identify biomarkers and therapeutic targets, ii) repurposing ...
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New biodegradable biomaterials for a variety of biomedical applications like wound healing, drug delivery etc. Design and develop new tunable immune-responsive biomaterials to control macrophage phenotype for achieving desirable clinical outcomes.
Our lab studies the role of DNA repair proteins in mediating germ cell development in mammals, the spermatogonial stem cell niche, DNA mismatch repair
I study taste and metabolism. I’m particularly interested in how feeding behaviors can be influenced by obesity and inflammation.
Research in the DeLisa group focuses on understanding and controlling the molecular mechanisms underlying protein biogenesis – folding and assembly, membrane translocation and post-translational modifications – in the complex environment of a living cell. ...
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The main focus of my research program is to elucidate key components in enveloped viruses and their host cells that: 1] mediate viral entry into cells, 2] elicit cell immune responses, and 3] mediate ...
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We are interested in the role of Tyrosine Kinases (TKs) in regulating the immune response, with the goal of using this information to manipulate immune responses. We are specifically interested in the Tec families ...
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