Our lab studies immune dysregulation in the disease Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, by examining physiology of immune cells, levels of cytokines and other signaling proteins, cargo of extracellular vesicles, mitochondrial genomes, and transcriptomes of ...
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Immune cell signaling.
Molecular and Cellular Mechanisms of Neurodegneration
We are interested in the genetic and environmental factors that regulate regulatory lymphocyte development and function, and how they interact to regulate immune homeostasis.
My research can be grouped into 3 broad categories: i) defining the role of DNA damage response mechanisms (DDR) in tumorigenesis and chemosensitivity as a means to identify biomarkers and therapeutic targets, ii) repurposing ...
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The main focus of my research program is to elucidate key components in enveloped viruses and their host cells that: 1] mediate viral entry into cells, 2] elicit cell immune responses, and 3] mediate ...
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We are interested in the role of Tyrosine Kinases (TKs) in regulating the immune response, with the goal of using this information to manipulate immune responses. We are specifically interested in the Tec families ...
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My lab focuses on the mechanisms that underlie microbiome-associated disorders. We apply systems biology and precision engineering to develop microbiome-base diagnostics and therapeutics.
My laboratory focuses on the impact of pathogens and the microbiota on body homeostasis. We use systemic infection as a model for septicemia, and the gut response to infection as a model for mucosal ...
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We are interested in understanding the impact of the gut microbiome, a vast population of microorganisms that inhabits our intestines, in regulating many aspects of human health and disease. To accomplish these goals, our ...
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