My research can be grouped into 3 broad categories: i) defining the role of DNA damage response mechanisms (DDR) in tumorigenesis and chemosensitivity as a means to identify biomarkers and therapeutic targets, ii) repurposing ...
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Dr. Diel’s research focuses the molecular mechanisms underlying virus-host interactions and more specifically on the mechanisms underlying viral immune evasion that contribute to virus virulence and disease pathogenesis. My goal in studying virus-host interactions ...
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My research program addresses 2 main interconnected areas: developmental immunology and immunodeficiencies, with focus on B cell generation and differentiation, and engaging discovery in basic immunology with direct application to clinical immunology. We study ...
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The Feschotte laboratory study transposons and endogenous viruses primarily in vertebrates, including humans. We seek to characterize the impact of these elements on the evolution and physiology of their host species – including disease ...
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Nutrition, infection, and inflammation in pregnancy Role of key micronutrients (iron, vitamin B12, folate) in the etiology of adverse perinatal outcomes (including anemia, infections, birth defects) Design of interventions to improve the health of ...
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The main focus of my research program is to elucidate key components in enveloped viruses and their host cells that: 1] mediate viral entry into cells, 2] elicit cell immune responses, and 3] mediate ...
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We are interested in the role of Tyrosine Kinases (TKs) in regulating the immune response, with the goal of using this information to manipulate immune responses. We are specifically interested in the Tec families ...
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My lab focuses on the mechanisms that underlie microbiome-associated disorders. We apply systems biology and precision engineering to develop microbiome-base diagnostics and therapeutics.
My laboratory focuses on the impact of pathogens and the microbiota on body homeostasis. We use systemic infection as a model for septicemia, and the gut response to infection as a model for mucosal ...
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We are interested in understanding the impact of the gut microbiome, a vast population of microorganisms that inhabits our intestines, in regulating many aspects of human health and disease. To accomplish these goals, our ...
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