Studying host-parasite interactions that involves disciplines like pathology, immunology, molecular biology and gastroenterology. Developing diagnostics for veterinary parasites/pathogens. Studying biodiversity of parasites of North American wildlife.
My lab tries to understand regulatory mechanisms of protein function, such as protein post-translational modifications and allosteric modulation, and to use the understanding to develop potential therapeutics for treating human diseases, including immune diseases.
My lab is currently focused on two areas of immunology, canine immune mediated disease and aging of the immune system. We are particularly interested in identifying mechanistic biomarkers to help improve, diagnosis, prognosis and ...
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Our lab is interested in developing advanced biomaterials for agricultural and biomedical applications with a particular focus on cell replacement therapies for type 1 diabetes (T1D). Most of our work, ranging from material synthesis ...
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Research/Clinical Interest Hemostasis / Thrombosis: Investigation of novel bleeding disorders, developing new assays for investigation of hemostatic defects, refining antithrombotic drug regimens. Sepsis: Development of novel biomarkers including through use of ‘Omics technologies. Antimicrobials: ...
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Dr. Guarino is interested in the development of novel serologic assays for the diagnosis of infection with viral and bacterial pathogens in companion and production animals. Of particular interest is the diagnosis of commonly ...
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Our lab studies immune dysregulation in the disease Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, by examining physiology of immune cells, levels of cytokines and other signaling proteins, cargo of extracellular vesicles, mitochondrial genomes, and transcriptomes of ...
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Immune cell signaling.
Molecular and Cellular Mechanisms of Neurodegneration
We are interested in the genetic and environmental factors that regulate regulatory lymphocyte development and function, and how they interact to regulate immune homeostasis.
