The structure and function of viral envelope proteins, how genomic mutations lead to changes in the envelope proteins and control viral pathogenesis in influenza viruses and coronaviruses,SARS-CoV, MERS-CoV and feline coronaviruses; novel vaccines and ...
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My group is interested in developing novel label-free cell assays by integrating vibrational spectroscopy, microfluidics, and dielectrophoresis. We apply these techniques to both adherent and non-adherent cells to elicit drug effects on various signalling ...
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Given that a) the majority of the world is either over- or under-nourished; and b) diet and nutrition-related factors represent the largest proportion of risk factors for global mortality and morbidity, we often use ...
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I develop optical tools for imaging the behavior of cells within in vivo preparations. I apply these tools in many systems, but have particular interests in studying the effects of microvascular dysfunction in the ...
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Ong’s current research interests include the social determinants of health in later adulthood, particularly the role of social isolation and loneliness; the pathways linking positive emotions to quality living and health morbidities in both ...
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My lab is interested in host-cell-virus interactions. We primarily study mammalian orthoreoviruses. Current projects include: mechanisms of viral compartmentalization and commandeering of the host translational machinery; viral mechanisms of counteracting the innate immune response; ...
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We study viruses of animals, focusing on those that have jumped from one host to another. The main subjects of study include the canine parvovirus, which emerged in 1978 to cause a pandemic in ...
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I am interested in the interaction between the immune and endocrine systems, in particular how tissue-specific immune cells in reproductive and endocrine tissues regulate hormone production and action.
My lab is focused on understanding basic principles of immunity against infection and age-related changes that alter immune responses in early life. We also are interested in determining how environmental factors (maternal diet, microbiome, ...
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