Mutant proteins linked to DNA damage, muscular dystrophy

Jan Lammerding is the senior author on new Cornell-led research paper which reports a strong connection between DNA damage triggered by mutations in proteins that surround the cell nucleus, known as lamins, and muscular dystrophy. By exploring the mechanisms that cause the damage, the researchers are hopeful their discovery can help shape better treatments. “Mutant Lamins Cause Nuclear Envelope Rupture and DNA Damage in Skeletal Muscle Cells,” was published Dec. 16 in Nature Materials.

Read the full article here.