Development of the adaptive immune response and integration of DNA damage responses and immune responses.
I am interested in host pathogen interactions in human retrovirus infections, including HIV-1 and human endogenous retroviruses.
We investigate (1) how UBR5, a novel protein ubiquitin ligase frequently altered in human cancers, promotes tumor metastasis by regulating epithelial to mesenchymal transition (EMT) in a cell intrinsic manner;(2) to identify UBR5â€™s E3 ...
Immunological aspects of pregnancy; Immunogenetics; Immunity to Infectious Diseases. Primary species focus on the horse.