Sleckman
Development of the adaptive immune response and integration of DNA damage responses and immune responses.
Development of the adaptive immune response and integration of DNA damage responses and immune responses.
I am interested in host pathogen interactions in human retrovirus infections, including HIV-1 and human endogenous retroviruses.
We investigate (1) how UBR5, a novel protein ubiquitin ligase frequently altered in human cancers, promotes tumor metastasis by regulating epithelial to mesenchymal transition (EMT) in a cell intrinsic manner;(2) to identify UBR5’s E3 ...
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Immunological aspects of pregnancy; Immunogenetics; Immunity to Infectious Diseases. Primary species focus on the horse.