The mammalian gastrointestinal tract is colonized with diverse commensal microbial communities consisting of bacteria, fungi and viruses. The Iliev Laboratory studies the interaction between this commensal microbiota and the immune cells at the mucosal ...
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Immune memory occurs when the immune system remembers previous encounters with pathogens, aberrant cells, or self-antigens to produce a more rapid or robust secondary response upon re-encounter. It stands as the cornerstone of vaccine ...
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My general research interest is immune regulation in dairy cows with a focus on the innate immune response in mastitis and metritis, 2 of the economically most important disease complexes in dairy cattle. The ...
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The focus and long-term research goals of the Sonnenberg Laboratory are to interrogate the mechanisms that maintain a state of health in the human gastrointestinal tract. Ongoing research in the Sonnenberg Laboratory aims to ...
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My lab is interested in host-cell-virus interactions. We primarily study mammalian orthoreoviruses. Current projects include: mechanisms of viral compartmentalization and commandeering of the host translational machinery; viral mechanisms of counteracting the innate immune response; ...
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The goal of Dr. Salmon’s research is to identify predictors and determinants of disease phenotype in systemic lupus erythematosus (SLE) and related diseases, and to thereby identify targets for therapy. In SLE and other ...
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Our lab studies Legionella infection and host interaction. Legionella are mainly environmental bacteria. Several species, in particular L. pneumophila and L. longbeachae, are pathogenic to humans Due to the development of artificial water systems, ...
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There is a fine balance between appropriate, host-protective, immune responses and dysregulated autoimmune and pathologic inflammation. The Leifer lab investigates how immune responses are induced and regulated with the hope of developing treatments to ...
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The Feschotte laboratory study transposons and endogenous viruses primarily in vertebrates, including humans. We seek to characterize the impact of these elements on the evolution and physiology of their host species – including disease ...
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The Blander Laboratory studies the mechanisms by which the innate immune system detects and responds to perturbations in homeostasis at the molecular, cellular and organismal level. We study these responses in the context of ...
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