Schimenti
My lab studies mechanisms of genome maintenance and consequences of genome instability. Such consequences include cancer, cellular senescence, impacts on stem cells, and lethal levels of inflammation.
Archives
Josefowicz
(1) Histone functional genetic models to study epigenetic regulation of mouse hematopoiesis and immune cell development. (2) Mechanisms and function of epigenetic memory of inflammation in hematopoietic stem cells. (3) “Signaling to chromatin” and ...
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Leifer
There is a fine balance between appropriate, host-protective, immune responses and dysregulated autoimmune and pathologic inflammation. The Leifer lab investigates how immune responses are induced and regulated with the hope of developing treatments to ...
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Loftus
My lab is currently focused on two areas of immunology, canine immune mediated disease and aging of the immune system. We are particularly interested in identifying mechanistic biomarkers to help improve, diagnosis, prognosis and ...
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Matei
My research focuses on deciphering the role of exosomes in mediating the crosstalk between the host immune system and the tumor, and the mechanisms through which exosomes coax the immune system to contribute to ...
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Finkelstein
Nutrition, infection, and inflammation in pregnancy Role of key micronutrients (iron, vitamin B12, folate) in the etiology of adverse perinatal outcomes (including anemia, infections, birth defects) Design of interventions to improve the health of ...
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Huang
We are interested in the genetic and environmental factors that regulate regulatory lymphocyte development and function, and how they interact to regulate immune homeostasis.
August
We are interested in the role of Tyrosine Kinases (TKs) in regulating the immune response, with the goal of using this information to manipulate immune responses. We are specifically interested in the Tec families ...
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Barrat
The main interest of the lab is centered on the basic understanding of nucleic acid recognition in autoimmunity and in particular on the potential clinical benefit of interfering with TLR signaling in human diseases. ...
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Blander
The Blander Laboratory studies the mechanisms by which the innate immune system detects and responds to perturbations in homeostasis at the molecular, cellular and organismal level. We study these responses in the context of ...
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