We study how Th17 cells develop in mouse and human, and how IL-17 functions to balance inflammatory and regulatory roles during infection and autoimmunity. We are particularly interested in understanding how IL-17 signaling in ...
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My current research explores epigenetic and environmental mechanisms of disease in the setting of the immune system with emphasis on the metabolic disease and interactions with infectious and neurological disease.
My general research interest is immune regulation in dairy cows with a focus on the innate immune response in mastitis and metritis, 2 of the economically most important disease complexes in dairy cattle. The ...
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I work on links between hemostasis, immunity and cancer and infectious diseases, particularly equine herpes virus type-1 in horses.
We are interested in the chemical biology of metabolism as a mediator of the host-pathogen interaction. We focus specifically on Mycobacterium tuberculosis and its ability to both asymptomatically infect and cause disease in humans.
My lab is focused on understanding basic principles of immunity against infection and age-related changes that alter immune responses in early life. We also are interested in determining how environmental factors (maternal diet, microbiome, ...
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The lab studies host-pathogen interactions, focusing on macrophages and Mycobacterium tuberculosis (Mtb). Most projects in the lab today fall into one or more of the following broad topics: host pathways controlling susceptibility and resistance ...
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There is a fine balance between appropriate, host-protective, immune responses and dysregulated autoimmune and pathologic inflammation. The Leifer lab investigates how immune responses are induced and regulated with the hope of developing treatments to ...
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Our lab studies Legionella infection and host interaction. Legionella are mainly environmental bacteria. Several species, in particular L. pneumophila and L. longbeachae, are pathogenic to humans Due to the development of artificial water systems, ...
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The lab is interested in the pathogenesis of Mycobacterium tuberculosis and explores the mechanisms by which this pathogen establishes and maintains persistent infections.
