The Mason laboratory develops and deploys computational and experimental methodologies to identify the functional genetic elements of the human genome and metagenome. To do this, we perform research in three principal areas: (1) molecular ...
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The Shen Lab lab investigates the genetic, epigenetic and metabolic mechanisms of cancer evolution. Our research is focused on understanding the role of PTEN in protecting the genome, maintaining chromatin architecture, suppressing tumorigenesis, and ...
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Dr. Ivashkiv’s laboratory investigates the pathogenic mechanisms of cytokines in inflammatory and musculoskeletal conditions such as rheumatoid arthritis, osteolysis and orthopaedic implant loosening/failure, and systemic lupus erythematosus. He is interested in how cytokines and ...
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(1) Histone functional genetic models to study epigenetic regulation of mouse hematopoiesis and immune cell development. (2) Mechanisms and function of epigenetic memory of inflammation in hematopoietic stem cells. (3) “Signaling to chromatin” and ...
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I am currently interested in employing predictive approaches (primarily through integrated analyses of public genomic datasets) that can be applied to various topics in cancer. These topics include: a) prediction of molecular markers for ...
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