I work on links between hemostasis, immunity and cancer and infectious diseases, particularly equine herpes virus type-1 in horses.
The objective of Dr. Gerlinde Van de Walle’s research is to open up new avenues towards therapeutic intervention by better understanding the pathogenesis of diseases important to veterinary and human medicine. To this end, ...
My lab aims at exploring the immune-metabolic role of radiation therapy and to define the impact of TGFb and activin A in the radiation response of glioblastomas.
My lab is interested in cytokines as therapeutics. Our goal is to control the immune system without using cells. We design polymers to extend the interleukin’s half-life in vivo.
The Shen Lab lab investigates the genetic, epigenetic and metabolic mechanisms of cancer evolution. Our research is focused on understanding the role of PTEN in protecting the genome, maintaining chromatin architecture, suppressing tumorigenesis, and ...
We explore epigenetic mechanisms that are required to drive the humoral immune response, and how disruption of these mechanisms cause malignant transformation into lymphomas.
I have been working on a new technology in immune-oncology field leveraging on my expertise in gene expression analysis and genetic engineering. Recently, I defined a correlation between ICAM-1 expression and malignant features in ...
I am interested in host pathogen interactions in human retrovirus infections, including HIV-1 and human endogenous retroviruses.
My lab studies mechanisms of genome maintenance and consequences of genome instability. Such consequences include cancer, cellular senescence, impacts on stem cells, and lethal levels of inflammation.
I am interested in the microbiome and how it impacts efficacy of immunotherapy and radiation. I am also studying prostate SBRT.