College of Agriculture & Life Sciences - Ithaca
Interests: Bacteria, Gene Regulation, Genetics / Genomics, Gut Microbiome, Host-Microbe Interaction, Host-Pathogen Interaction, Innate Immunity, Microbiome, Microbiota, Mucosal Immunology, Pathogenesis, Stem Cells
My laboratory focuses on the impact of pathogens and the microbiota on body homeostasis. We use systemic infection as a model for septicemia, and the gut response to infection as a model for mucosal immunity. Genomic and genetic approaches allow us to characterize new pathways involved in both resistance and resilience/tolerance to infection. We are particularly interested in the three way dialogue between gut microbes, intestinal stem cells, and gut structure and function.