The mammalian gastrointestinal tract is colonized with diverse commensal microbial communities consisting of bacteria, fungi and viruses. The Iliev Laboratory studies the interaction between this commensal microbiota and the immune cells at the mucosal ...
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Immune memory occurs when the immune system remembers previous encounters with pathogens, aberrant cells, or self-antigens to produce a more rapid or robust secondary response upon re-encounter. It stands as the cornerstone of vaccine ...
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We study how Th17 cells develop in mouse and human, and how IL-17 functions to balance inflammatory and regulatory roles during infection and autoimmunity. We are particularly interested in understanding how IL-17 signaling in ...
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I study primary macrophages as targets of viral infection, including HIV and SARS-CoV2. I am using advanced ex vivo analyses, unbiased and targeted molecular profiling and mouse genetics to dissect the roles of macrophages ...
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Regulation of Immunity at Tissue Sites of Infection and Autoimmunity.
The structure and function of viral envelope proteins, how genomic mutations lead to changes in the envelope proteins and control viral pathogenesis in influenza viruses and coronaviruses,SARS-CoV, MERS-CoV and feline coronaviruses; novel vaccines and ...
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The lab studies host-pathogen interactions, focusing on macrophages and Mycobacterium tuberculosis (Mtb). Most projects in the lab today fall into one or more of the following broad topics: host pathways controlling susceptibility and resistance ...
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My lab is interested in host-cell-virus interactions. We primarily study mammalian orthoreoviruses. Current projects include: mechanisms of viral compartmentalization and commandeering of the host translational machinery; viral mechanisms of counteracting the innate immune response; ...
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