In my lab we use molecular and genome-scale approaches to gain insight into normal physiology and disease etiology, primarily in the digestive system (gastrointestinal tract, liver, and pancreas). We are particularly interested in defining ...
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Although immune checkpoint blockade therapy has revolutionized cancer treatment, a subset of tumors, such as those of the breast, are still largely unresponsive. The Dongre Lab is focused on understanding mechanisms that can potentiate ...
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We are interested in the role of the immune system in the initiation, progress and recurrence of skin cancer.
The goals of our work are to improve understanding of cardiac diseases in veterinary species, particularly infectious disease. The diagnosis of myocarditis or sudden death in veterinary species is frustratingly incomplete due to a ...
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Regulation of Myelo- monopoiesis by chemo lines and hormones including retinoic acid
My lab studies mechanisms of genome maintenance and consequences of genome instability. Such consequences include cancer, cellular senescence, impacts on stem cells, and lethal levels of inflammation.
Our lab studies the role of DNA repair proteins in mediating germ cell development in mammals, the spermatogonial stem cell niche, DNA mismatch repair
