In my lab we use molecular and genome-scale approaches to gain insight into normal physiology and disease etiology, primarily in the digestive system (gastrointestinal tract, liver, and pancreas). We are particularly interested in defining ...
Read More
We study how gene expression patterns are encoded in Metazoan DNA sequence, and how these patterns contribute to evolution, development, and disease.
My lab is focused on understanding how bioactive lipids contribute to diet-microbiome and microbiome-host interactions. We use techniques in molecular biology, mass spectrometry, microbial genetics, and genomics to understand the consequences of lipid transfer ...
Read More
Regulation of Myelo- monopoiesis by chemo lines and hormones including retinoic acid
The Mason laboratory develops and deploys computational and experimental methodologies to identify the functional genetic elements of the human genome and metagenome. To do this, we perform research in three principal areas: (1) molecular ...
Read More
The Shen Lab lab investigates the genetic, epigenetic and metabolic mechanisms of cancer evolution. Our research is focused on understanding the role of PTEN in protecting the genome, maintaining chromatin architecture, suppressing tumorigenesis, and ...
Read More
The structure and function of viral envelope proteins, how genomic mutations lead to changes in the envelope proteins and control viral pathogenesis in influenza viruses and coronaviruses,SARS-CoV, MERS-CoV and feline coronaviruses; novel vaccines and ...
Read More
We are interested in the chemical biology of metabolism as a mediator of the host-pathogen interaction. We focus specifically on Mycobacterium tuberculosis and its ability to both asymptomatically infect and cause disease in humans.
My lab studies mechanisms of genome maintenance and consequences of genome instability. Such consequences include cancer, cellular senescence, impacts on stem cells, and lethal levels of inflammation.
The research interests of the lab fall under the broad categories of genomics, computational biology and systems biology. We participate in multiple international genomics consortia and collaborate with scientists at multiple institutes to develop ...
Read More
