My lab tries to understand regulatory mechanisms of protein function, such as protein post-translational modifications and allosteric modulation, and to use the understanding to develop potential therapeutics for treating human diseases, including immune diseases.
Our lab studies Legionella infection and host interaction. Legionella are mainly environmental bacteria. Several species, in particular L. pneumophila and L. longbeachae, are pathogenic to humans Due to the development of artificial water systems, ...
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Insulin regulates the storage of dietary glucose by stimulating its uptake into muscle and fat. Insulin increases glucose uptake into these cells by recruiting vesicles containing the GLUT4 glucose transporter to the cell surface. ...
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Immune cell signaling.
