Development of the adaptive immune response and integration of DNA damage responses and immune responses.
We explore epigenetic mechanisms that are required to drive the humoral immune response, and how disruption of these mechanisms cause malignant transformation into lymphomas.
I am interested in host pathogen interactions in human retrovirus infections, including HIV-1 and human endogenous retroviruses.
Our laboratory has had a longstanding interest in understanding the molecular mechanisms employed by lymphocytes to accurately respond to the signals that guide them along specific pathways.
My research program addresses 2 main interconnected areas: developmental immunology and immunodeficiencies, with focus on B cell generation and differentiation, and engaging discovery in basic immunology with direct application to clinical immunology. We study ...
The Blander Laboratory studies the mechanisms by which the innate immune system detects and responds to perturbations in homeostasis at the molecular, cellular and organismal level. We study these responses in the context of ...