Immune memory occurs when the immune system remembers previous encounters with pathogens, aberrant cells, or self-antigens to produce a more rapid or robust secondary response upon re-encounter. It stands as the cornerstone of vaccine ...
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My lab is focused on understanding basic principles of immunity against infection and age-related changes that alter immune responses in early life. We also are interested in determining how environmental factors (maternal diet, microbiome, ...
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(1) Histone functional genetic models to study epigenetic regulation of mouse hematopoiesis and immune cell development. (2) Mechanisms and function of epigenetic memory of inflammation in hematopoietic stem cells. (3) “Signaling to chromatin” and ...
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Our laboratory studies antibody-mediated immune responses to the protozoan parasite, Ichthyophthirius multifiliis, a major pathogen of freshwater fish. We have additional interests in the production of recombinant membrane proteins more generally as subunit vaccines ...
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